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. 2018 Feb 20;8:3327. doi: 10.1038/s41598-018-21769-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Estimation of Bcl-2 and Bax expression in T lymphocytes. Figure A shows expression of Bcl-2 protein measured as mean fluorescence intensity (MFI), Figure B - expression of Bax protein and Figure C - Bax-Bcl-2 ratio in healthy people and BD patients. Center lines of figures present medians, boxes present 25th-75th percentiles and whiskers show the minimal and maximal values observed, Mann-Whitney test, *p < 0.05. Figure D and E respectively show fold change in BCL2 and BAX genes’ expression.