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. 2018 Feb 20;8:3375. doi: 10.1038/s41598-018-21659-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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AC026166.2-001 inhibits cell proliferation and colony formation by LSCC cells. (A) Overexpression of AC026166.2-001 in LSCC cell lines was analyzed by qRT-PCR. (B) AC026166.2-001 significantly inhibited proliferation rates during a period of 96 h determined by RTCA. (C) AC026166.2-001 reduced the colony formation capacity of AMC-HN-8 and TU-212 cells. (D) AC026166.2-001 expression was examined in NC (non-transfected control) and siRNA transfected LSCC cells by qRT-PCR. (E) Cell proliferation was determined in siRNA-NC and AC026166.2-001-siRNA-1-transfected AMC-HN-8 and TU-212 cells by RTCA during a period of 96 h. (F) Colony formation capacity of siRNA-NC and AC026166.2-001-siRNA-1-transfected AMC-HN-8 and TU-212 cells.