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. 2018 Feb 20;8:3341. doi: 10.1038/s41598-018-21716-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Challenge commonly faced when designing an fNIRS experiment to assess a set of regions of interest expected to be activated according to a study hypothesis: the translation to an fNIRS optode layout by choosing appropriate sources and detectors positions to maximize anatomical specificity to regions of interest. Illustrated are Brodmann areas 4, 9 and 19 and 21 and the fNIRS cap layout with corresponding color-coded channels.