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. 2017 Feb 21;28(1):1–15. doi: 10.1007/s10926-016-9690-x

Table 2.

Characteristics of studies

Study author (year) QA rating Intervention domain Country Study design Population Sample size Loss to follow-up Length of observation
Cheng (2007)
High
Health focused Hong Kong Randomized trial MSK/pain i1 = 46
c1 = 48
Not provided 4 weeks
Linton (1992)
Moderate
Health focused Sweden Randomized trial MSK/pain i1 = 36
c1 = 30
Not provided 6 months (all subjects)
18 months (i1)
Norrefalk (2005)
Moderate
Health focused Sweden Non-randomized trial MSK/pain i1 = 72
c1 = 14
i1 = 5
c1 = Not provided
1 year
Lidstrom (1992)
High
Health focused Sweden Randomized trial MSK/pain i1 = 51
c1 = 52
Not provided 2 years
Hlobil 2005
High
Health focused The Netherlands Randomized trial MSK/pain i1 = 67
c1 = 67
i1 = 0
c1 = 0
1 year (RTW)
3 years (costs)
Verbeek (2002)
High
Health focused The Netherlands Randomized trial MSK/pain i1 = 61
c1 = 59
Not provided 1 year
Whitfill (2010)
High
Health focused USA Randomized trial MSK/Pain i1 = 58
c1 = 44
Not provided 1 year
Haig (1990)
Moderate
Service coordination USA Cohort with historical comparison MSK/pain i1 = 61
c1 = 52
Not provided 1 year
McCluskey (2006)
Moderate
Service coordination United Kingdom Non-randomized trial MSK/pain i1 = 81
i2 = 223
c1 = 214
Not provided 1 year
Ryan (1995)
Moderate
Service coordination Australia Cohort with concurrent comparison MSK/pain Not provided Not provided 6 years
van Oostrom (2010)
High
Service coordination The Netherlands Randomized trial Mental health i1 = 73
c1 = 72
i1 = 0
c1 = 2
1 year
Anema (2004)
Moderate
Work modification Denmark, Germany, Israel, the Netherlands, Sweden & USA Cohort with concurrent comparison MSK/pain i1 = 206, i2 = 299, i3 = 270
c1 = 311, c2 = 244, c3 = 291
Not provided 2 years
Hanson (2001)
Moderate
Work modification USA Cohort with concurrent comparison MSK/pain i1 = 14, i2 = 29
c1 = 14
Not provided 1 year
Viikari-Juntura (2012)
High
Work modification Finland Randomized trial MSK/pain i1 = 32
c1 = 31
i1 = 1
c1 = 5
1 year
Shaw (2006)
Moderate
Work modification USA Randomized trial MSK/pain i1 = 11
c1 = 12
Not provided 14 months
Bernacki (2003)
Moderate
Multi-domain USA Cohort with historical comparison MSK/pain i1 = 17k to 28k per annum (1993 to 1999)
c1 = 16k to 17k per annum (1989 to 1992)
Not provided 10 years
Beutel (2005)
Moderate
Multi-domain Germany Randomized trial Mental health i1 = 179
c1 = 87
i1 = 83
c1 = 2
2 years
Davis (2004)
Moderate
Multi-domain Canada Cohort with historical and concurrent comparison MSK/pain i1 = 90
c1(hist.) = 345
c2(con.) = 53
Not provided 6 months
Jensen (1998)
High
Multi-domain Sweden Cohort with concurrent comparison MSK/pain i1 = 67
c1 = 29
i1 = 9
c1 = 4
18 months
Lambeek (2010)
High
Multi-domain The Netherlands Randomized trial MSK/pain i1 = 66
c1 = 68
i1 = 3
c1 = 7
1 year
Larson (2011)
Moderate
Multi-domain USA Cohort with historical comparison MSK/pain i1 = 661
c1 = 713
Not provided 8 weeks
Nordstrom-Bjorverud (1998)
Moderate
Multi-domain Sweden Cohort with historical comparison MSK/pain i1 = 34
c1 = 72
i1 = 0
c1 = 15
2–4 years
(median: 2.8 years)
Yassi (1995)
Moderate
Multi-domain Canada Non-randomized trial MSK/pain i1 = 60
c1 = 158
Not provided 2 years
Jensen (2013)
High
Multi-domain Denmark Non-randomized trial MSK/pain, mental health i1 = 114
c1 = 86
i1 = 27
c1 = Not provided
2 years
Karlson (2010)
Moderate
Multi-domain Sweden Non-randomized trial Mental health i1 = 74
c1 = 74
i1 = 0
c1 = 0
18 months
Anema (2007)
Moderate
Health focused (i2), Work modification (i1), Multi-domain (i3) The Netherlands Randomized trial MSK/pain i1 = 96, i2 = 55, i3 = 27
c1 = 100, c2 = 57, c3 = 85
i1 = 10, i2 = 19,
i3 = Not provided
c1 = 0, c2 = 0, c3 = 0
1 year
Blonk (2006)
Moderate
Health focused (i1), Multi-domain (i2) The Netherlands Randomized trial Mental health i1 = 40, i2 = 40
c1 = 42
i1 = 10, i2 = 10
c1 = 13
1 year
Hees (2013)
High
Health focused (c1), Multi-domain (i1) The Netherlands Randomized trial Mental health i1 = 78
c1 = 39
i1 = 10
c1 = 6
18 months
Vlasveld (2013)
High
Health focused (c1), Multi-domain (i1) The Netherlands Randomized trial Mental health i1 = 65
c1 = 61
i1 = 21*
c1 = 31*
1 year
Arends (2013)
High
Health focused (c1), Multi-domain (i1) The Netherlands Randomized trial Mental health i1 = 80
c1 = 78
i1 = 23*
c1 = 28*
1 year
Kroger (2015)
High
Health focused (c1), Multi-domain Germany Non-randomized trial Mental health i1 = 13
c1 = 13
i1 = 0
c1 = 0
1 year
Lagerveld (2012)
High
Health focused (c1), Multi-domain (i1) The Netherlands Non-randomized trial Mental health i1 = 105
c1 = 103
i1 = 30
c1 = 23
1 year
Schene (2007)
High
Health focused (c1), Multi-domain (i1) The Netherlands Randomized trial Mental health i1 = 32
c1 = 30
i1 = 8
c1 = 5
3.5 years
Karjalainen (2003)
High
Health focused (i1), Multi-domain (i2) Finland Randomized trial MSK/pain i1 = 58
i2 = 55
c1 = 57
i1 = 0
i2 = 2
c1 = 3
2 years
Lemstra (2004)
Moderate
Health focused (i2), Multi-domain (i1) Canada Cohort with historical and concurrent comparison MSK/pain i1 = 232, i2 = 232
c1 = 185, c2 = 285
Not provided 3 years
Loisel (1997)
High
Health focused (i1), Work modification (i2), Multi-domain (i3) Canada Randomized trial with cross-over MSK/pain i1 = 31, i2 = 22, i3 = 25
c1 = 26
Not provided 6.4 years

i intervention group, c comparison group, hist historical, con concurrent

*Loss to follow-up only affected self-report measures. RTW data was available for all participants