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Involvement of AMPK in the inhibitory effects of nobiletin on lipid accumulation. The protein expression levels of phosphorylated AMPK (a), phosphorylated ACC (b), SREBP-1c (c), and FAS (d). Values are expressed as the means ± standard errors (n = 3). ∗p < 0.05 versus high glucose-treated cells; #p < 0.05 versus control; ∗∗p < 0.05 versus high glucose plus 50 μM nobiletin-treated cells. Blots are representative of at least three independent experiments.
