Table 2.
Effects of GJE on MMP-2 and MMP-9 gene expression in colon cancer cells. HT-29 and SW-480 colon cancer cells were treated with GJE for 24 h; MMP-2 and MMP-9 mRNA levels were analyzed by quantitative real-time PCR. Results are expressed as the percentage of expression versus control condition. Data represent means ± SEM from three independent experiments. ∗p < 0.001 versus control.
| HT-29 | SW-480 | |||
|---|---|---|---|---|
| AR | RB | AR | RB | |
| MMP-2 | 61.6 ± 1.1∗ | 56.8 ± 4.7∗ | 90.4 ± 3.9∗ | 96.3 ± 2.8∗ |
| MMP-9 | 94.9 ± 3.6∗ | 97.3 ± 2.4∗ | 95.3 ± 4.1∗ | 91.3 ± 6.4∗ |