Table 2.
Effects of L-theanine treatment on the cytokines secretion in rat splenic lymphocytes.
| Item | Control | ConA | ConA + LTHs | P value | ||
|---|---|---|---|---|---|---|
| 0.25 mM | 1 mM | 4 mM | ||||
| IFN-γ (ng/gprotein) | 0.24 ± 0.02e | 0.94 ± 0.04d | 0.99 ± 0.03c | 1.25 ± 0.03b | 1.37 ± 0.05a | <0.01 |
| IL-2 (ng/gprotein) | 2.60 ± 0.19d | 5.52 ± 0.16c | 6.27 ± 0.35b | 5.46 ± 0.17c | 7.20 ± 0.26a | <0.01 |
| IL-4 (ng/gprotein) | 2.45 ± 0.05e | 29.00 ± 0.2b | 24.05 ± 0.17d | 27.83 ± 0.22c | 31.7 ± 0.31a | <0.01 |
| IL-6 (ng/gprotein) | 0.21 ± 0.03b | 0.36 ± 0.04b | 0.33 ± 0.02b | 0.35 ± 0.01b | 0.39 ± 0.02a | <0.01 |
| IL-10 (ng/gprotein) | 1.70 ± 0.37d | 3.66 ± 0.38a | 3.43 ± 0.50a | 2.51 ± 0.16c | 3.02 ± 0.28b | <0.01 |
| IL-12 (ng/gprotein) | 10.24 ± 1.98d | 44.15 ± 3.2b | 36.24 ± 1.86c | 35.00 ± 1.81c | 52.09 ± 2.45a | <0.01 |
| TNF-α (ng/gprotein) | 2.49 ± 0.19d | 4.09 ± 0.2a | 3.52 ± 0.16b | 3.08 ± 0.23c | 4.25 ± 0.18a | <0.01 |
a–e Means in the same row not bearing a common superscript letter differ (P < 0.05); ConA = concanavalin A activation group; LTHs = L-theanine treatments.