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. 2017 Dec 26;318(24):2466–2482. doi: 10.1001/jama.2017.19344

Figure 4. Meta-analysis Results of Combined Calcium and Vitamin D Supplementation for the Incidence of Hip, Nonvertebral, Vertebral, and Total Fractures.

Figure 4.

Size of data markers is proportional to the weight of each trial. Risk ratios and 95% CIs were calculated using the Mantel-Haenszel method, with a random-effects model used to pool data. Error bars indicate 95% CIs. Risk ratio data are rounded to 2 decimal places; error bars reflect unrounded values. Trials with zero events in both the intervention and control groups are not included in the meta-analysis.