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. 2017 Nov 6;177(12):1774–1780. doi: 10.1001/jamainternmed.2017.5512

Table 2. Incidence Rate Ratio of Cancer in Warfarin Users vs Nonusers.

Cancer Site IRR (95% CI)
All cancers 0.84 (0.82-0.86)
Prostate 0.69 (0.65-0.72)
Lung 0.80 (0.75-0.86)
NSCLC 0.80 (0.74-0.87)
SCLC 0.71 (0.59-0.86)
Colon 0.99 (0.93-1.06)
Breast 0.90 (0.82-1.00)
Ductal 0.90 (0.81-1.02)
Lobular 1.00 (0.75-1.32)
Skina 1.09 (1.01-1.18)
Gynecological 0.85 (0.74-0.97)
Ovary 0.81 (0.65-1.02)
Uterus 0.91 (0.77-1.08)
Cervix 1.03 (0.69-1.54)
Vulva and vagina 0.64 (0.39-1.04)
Bone marrow 1.00 (0.91-1.10)
Leukemia 0.99 (0.89-1.11)
CLL 0.89 (0.71-1.11)
AML 0.70 (0.51-0.98)
Bladder 0.82 (0.75-0.90)
Malignant melanoma 0.96 (0.87-1.07)
Rectum and anus 0.77 (0.69-0.86)
Rectum 0.76 (0.68-0.85)
Anus 0.90 (0.51-1.58)
Lymphoma 0.92 (0.82-1.04)
Hodgkin 0.66 (0.34-1.26)
Non-Hodgkin 0.92 (0.81-1.04)
Brain 0.74 (0.64-0.87)
Astrocytoma 0.75 (0.57-0.98)
Meningioma 0.66 (0.51-0.86)
Glioblastoma 0.75 (0.56-1.00)
Kidney and ureters 0.93 (0.82-1.06)
Kidney 0.96 (0.84-1.10)
Pancreas 0.92 (0.80-1.04)
Stomach 0.77 (0.65-0.90)
Head and neck 0.64 (0.51-0.81)
Tongue 0.30 (0.16-0.56)
Throat 0.59 (0.39-0.90)
Larynx 0.75 (0.55-1.04)
Salivary gland 1.34 (0.74-2.41)
Mouth 0.80 (0.56-1.14)
Esophagus 1.03 (0.83-1.27)
Gallbladder 0.94 (0.71-1.24)
Endocrine glandsb 0.53 (0.36-0.80)
Thyroid 0.81 (0.56-1.18)

Abbreviations: AML, acute myeloid leukemia; CLL, chronic lymphatic leukemia; IRR, incidence rate ratio (adjusted for sex and age); NSCLC, non–small-cell lung cancer; SCLC, small-cell lung cancer.

a

Excluding malignant melanoma and basal cell carcinoma.

b

Excluding thyroid.