Figure 2.

I/R injury caused by cold ischemia and warm ischemia can produce common and specific effects on various subsets of cells. For example, sinusoidal endothelial cells are more susceptible than hepatic parenchymal cells to the effects of cold preservation, and the reperfusion phase amplifies the ischemic injury with the preferential involvement of the hepatic parenchymal cells; A- space of Disse; B- sinusoid; C- sinusoidal endothelial cells (with fenestrae); D- biliary canaliculus; E- Stellate cell; F- Kupffer cell; H- hepatocyte; N- nucleus.