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. 2018 Jan 1;9(3):535–539. doi: 10.7150/jca.22681

Table 2.

Stratification analysis for the association between NEFL gene polymorphisms and neuroblastoma susceptibility for combined subjects

Variables rs11994014 G>A rs2979704 T>C rs1059111 A>T
GG AG/AA Adjusted OR a P a TT CT/CC Adjusted OR a P a AA AT/TT Adjusted OR a P a
(Cases/Controls) (95% CI) (Cases/Controls) (95% CI) (Cases/Controls) (95% CI)
Age, month
≤18 48/120 76/185 1.03 (0.67-1.58) 0.903 48/117 76/188 0.99 (0.64-1.51) 0.947 48/118 76/187 1.00 (0.65-1.53) 0.997
>18 82/181 167/326 1.13 (0.82-1.56) 0.451 83/182 166/325 1.12 (0.81-1.54) 0.487 84/182 165/325 1.10 (0.80-1.51) 0.559
Gender
Females 50/135 107/207 1.40 (0.94-2.09) 0.099 50/131 107/211 1.33 (0.89-1.99) 0.161 50/132 107/210 1.35 (0.90-2.01) 0.143
Males 80/166 136/304 0.93 (0.66-1.30) 0.662 81/168 135/302 0.93 (0.66-1.30) 0.657 82/168 134/302 0.91 (0.65-1.27) 0.574
Sites of origin
Adrenal gland 49/301 85/511 1.02 (0.70-1.49) 0.918 50/299 84/513 0.98 (0.67-1.43) 0.918 50/300 84/512 0.98 (0.67-1.44) 0.933
Retroperitoneal 24/301 63/511 1.53 (0.93-2.50) 0.092 24/299 63/513 1.52 (0.93-2.48) 0.098 25/300 62/512 1.44 (0.89-2.34) 0.142
Mediastinum 39/301 70/511 1.07 (0.70-1.62) 0.764 39/299 70/513 1.05 (0.69-1.59) 0.822 39/300 70/512 1.06 (0.70-1.60) 0.797
Others 14/301 21/511 0.88 (0.44-1.76) 0.719 14/299 21/513 0.87 (0.44-1.74) 0.696 14/300 21/512 0.88 (0.44-1.75) 0.709
Clinical stages
I+II+4s 53/301 111/511 1.25 (0.87-1.78) 0.230 55/299 109/513 1.16 (0.81-1.65) 0.412 55/300 109/512 1.17 (0.82-1.66) 0.392
III+IV 70/301 119/511 1.01 (0.72-1.40) 0.978 70/299 119/513 1.00 (0.72-1.39) 0.985 70/300 119/512 1.00 (0.72-1.39) 0.998

OR, odds ratio; CI, confidence interval. a Adjusted for age and gender, omitting the corresponding stratification factor.