Table 4.
Adverse events | Nimotuzumab | Non-nimotuzumab | Z | P | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | 0 | 1 | 2 | 3 | 4 | |||
Hematologic | ||||||||||||
Leukopenia | 10 | 31 | 45 | 23 | 11 | 8 | 39 | 38 | 22 | 13 | -0.862 | 0.389 |
Neutropenia | 12 | 24 | 38 | 20 | 26 | 14 | 26 | 36 | 16 | 28 | -0.329 | 0.742 |
Anemia | 83 | 26 | 8 | 3 | 0 | 86 | 22 | 10 | 2 | 0 | -0.353 | 0.724 |
Thrombocytopenia | 111 | 3 | 4 | 2 | 0 | 108 | 4 | 5 | 3 | 0 | -0.687 | 0.492 |
Liver function | 81 | 24 | 15 | 0 | 0 | 79 | 27 | 12 | 2 | 0 | -0.225 | 0.822 |
Renal function | 112 | 6 | 2 | 0 | 0 | 115 | 5 | 0 | 0 | 0 | -0,877 | 0.380 |
Non-hematologic | ||||||||||||
Mucositis | 105 | 10 | 5 | 0 | 0 | 107 | 11 | 2 | 0 | 0 | -0.459 | 0.646 |
Dermatitis | 114 | 6 | 0 | 0 | 0 | 117 | 3 | 0 | 0 | 0 | -1.017 | 0.309 |
Diarrhea | 106 | 10 | 3 | 1 | 0 | 112 | 6 | 2 | 0 | 0 | -1.349 | 0.177 |
Nausea/vomiting | 87 | 22 | 10 | 1 | 0 | 88 | 18 | 12 | 2 | 0 | -0.002 | 0.998 |
Abbreviations: IC induction chemotherapy.