TABLE 2.
Distribution of TMEM173 HAQ and TMEM173 R232H in patients grouped according to severity of pneumonia
| Parameter | Severitya |
P valueb | ||
|---|---|---|---|---|
| Low (CURB-65 = 0–1) | Middle (CURB-65 = 2) | High (CURB-65 = 3–5) | ||
| Proportion female [% (n)] | 42.6 (23) | 45.4 (10) | 83.3 (5) | 0.37 |
| Age [yr; median (range)] | 57.5 (37–94) | 74 (36–94) | 73 (72–81) | 0.004 |
| TMEM173 HAQ [% (n)] | ||||
| Haplotype carrier | 27.8 (15) | 13.6 (3) | 50 (3) | 0.778 |
| TMEM173 R232H [% (n)] | ||||
| Haplotype carrier | 18.5 (10) | 36.4 (8) | 33.3 (2) | 0.256 |
a
Severity was defined by following the guidelines of the British Thoracic Society (34). From 87 patients initially included in the study, 5 were not considered for this analysis, as information regarding pneumonia severity was not available.
b
Significance was evaluated through an ordered logistic regression model.