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. 2018 Feb 16;5:30. doi: 10.3389/fmed.2018.00030

Figure 1.

Figure 1

Cell proliferation induction by Ov-GRN-1 with human umbilical vein endothelial cells (HUVECs). (A) Normalized cell index (nCI) output of the xCELLigence system of treatments of 5–20 nM Ov-GRN-1 on HUVECs cells over 70 h. (B) nCI relative to medium only negative controls (0 nM Ov-GRN-1) from (A) is plotted to highlight the first 24 h after treatment. RM two-way ANOVA with Holm–Sidak’s multiple comparison test of Ov-GRN-1 treatment vs medium only control at each time point: ns = not significant; *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. Data points are average values of four biological replicates and have been nudged ±0.2–1 h to ensure that SE bars are visible.