Table 3.

Endocrinological parameters before and after 2 months of vitamin D suppletion.

Parameter	At time of inclusion – median (IQR)	After 2 months of suppletion – median (IQR)	P valuea
Vitamin D (nmol/L)
VIDD with SHPT	20 (18–24)	108 (92–140)	<0.01
VIDD	20 (18–24)	111 (94–162)	<0.01
Controls	74 (59–87)	75 (66–89)	0.07
PTH (pmol/L)
VIDD with SHPT	14.1 (12.1–17.2)	9.3 (7.2–11.3)	<0.01
VIDD	12.0 (7.7–15.7)	7.4 (5.7–10.5)	<0.01
Controls	6.7 (5.3–9.0)	7.3 (6.0–9.7)	0.13
Calcium (mmol/L)
VIDD with SHPT	2.30 (2.20–2.36)	2.32 (2.26–2.42)	<0.01
VIDD	2.31 (2.24–2.38)	2.34 (2.29–2.44)	<0.01
Controls	2.33 (2.29–2.41)	2.35 (2.27–2.43)	0.65
Phosphate (mmol/L)
VIDD with SHPT	1.0 (0.9–1.1)	1.1 (1.0–1.2)	0.01
VIDD	1.0 (0.9–1.1)	1.1 (0.9–1.2)	0.02
Controls	1.0 (0.9–1.2)	1.0 (1.0–1.1)	0.43
Creatinine (µmol/L)
VIDD with SHPT	65 (57–70)	65 (58–72)	0.14
VIDD	65 (59–72)	65 (60–72)	0.13
Controls	67 (62–73)	65 (59–75)	0.74
Albumin (g/L)
VIDD with SHPT	37 (35–38)	36 (34–40)	0.49
VIDD	37 (35–39)	38 (35–40)	0.99
Controls	38 (36–40)	38 (36–40)	0.99
CRP (mg/L)
VIDD with SHPT	1.8 (1.0–6.0)	2.6 (0.7–6.0)	0.24
VIDD	1.9 (0.8–5.7)	2.6 (0.7–5.6)	0.34
Controls	1.5 (0.6–4.8)	2.1 (0.9–5.9)	0.01

Data are expressed as median (interquartile range). P-values < 0.05 are in bold. P values were rounded to 2 decimals. Null hypotheses: there are no statistically significant differences between the time of inclusion and after two months of vitamin D suppletion.

aWilcoxon signed rank test.

IQR, interquartile range; VIDD, vitamin D deficiency; SHPT, secondary hyperparathyroidism; PTH, parathyroid hormone; CRP, C-reactive protein.