Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The association of SHP2 mRNA level with the response to TKI therapy in lung adenocarcinoma patients.
| The response to TKI therapy | ||||
|---|---|---|---|---|
| Variables | Patient No. | Unfavorable (%) | Favorable (%) | P |
| SHP2 | ||||
| Low | 18 | 7 (39) | 11 (61) | 0.044 |
| High | 18 | 13 (72) | 5 (28) | |
The unfavorable response is defined at least 25% increase in size or number of the tumors; otherwise is defined as a favorable response. The median value of SHP2 mRNA levels was used as cutoff point to divide patients into “high” and “low” subgroups.
