Fig. 4.
(A) Genetic risk score for lupus was significantly higher in African-American compared to European-American lupus patients. (B) Correlation of SLEDAI score with CD4+CD28+KIR+CD11ahi T cell subset size and CD4+CD28+KIR+CD11ahi T cell subset size normalized by genetic risk score in European-American lupus patients stratified by age (n = 68). (C) Correlation of SLEDAI score with CD4+CD28+KIR+CD11ahi T cell subset size normalized by genetic risk score in European-American and African-American lupus patients (age ≤40 or >40 years) using linear regression. r: correlation coefficient; P: two-tailed t-test P-value. n = number of patients included in regression analysis.