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. Author manuscript; available in PMC: 2018 Feb 21.
Published in final edited form as: Methods Mol Biol. 2016;1389:111–126. doi: 10.1007/978-1-4939-3302-0_7

Figure 6. Segregated hybridization signal.

Figure 6

The images show CEP8 SpectrumGreen probe from a healthy donor where all events should contain two spots. Three spots (left image) or four spots (right image) can be observed but the intensity and proximity of the spots indicate that segregated hybridization has occurred. These examples would be classified as a disomy by conventional FISH.