Malaria is endemic in the countries highlighted in light blue. Resistance to
antimalarial drugs such as chloroquine (CQ) and pyrimethamine is widespread
(darker blue), while resistance to artemisinin-based combination therapies
(ACTs) is spreading. A new P. falciparum strain, PfPailin, that
is resistant to artemisinin plus piperaquine, has been found. Data presented in
the map are adapted from (7, 8).