Table 1.
Total (n=47) | Carotid Occlusion (n= 19) | Carotid Stenosis (n= 28) | P-value | |
---|---|---|---|---|
Mean Age, [SD] | 66 [10] | 62 [9] | 69 [10] | .02 |
Women, (%) | 19 (40) | 7 (35) | 12 (41) | .68 |
Black, (%) | 12 (25) | 5 (26) | 7 (25) | .92 |
Past Medical History | ||||
Hypertension, (%) | 38 (79) | 15 (79) | 22 (79) | .98 |
Hyperlipidemia, (%) | 34 (72) | 15 (79) | 19 (68) | .40 |
Coronary artery disease, (%) | 7 (15) | 2 (11) | 5 (18) | .49 |
Diabetes, (%) | 16 (34) | 2 (11) | 14 (50) | .01 |
Current or former smoker, (%) | 34 (72) | 16 (84) | 18 (64) | .24 |
Prior stroke or transient ischemic attack, (%) | 13 (28) | 9 (47) | 4 (14) | .01 |
Peripheral vascular disease, (%) | 3 (6) | 0 | 3 (11) | .14 |
Clinical Presentation | ||||
Ischemic stroke, (%) | 39 (81) | 18 (95) | 21 (75) | .17 |
Median admission NIH stroke scale [IQR] |
6 [2–12] | 7 [5–12] | 4 [2–13] | .44 |
Contralateral carotid stenosis, (%) | 10 (21) | 2 (11) | 8 (29) | .14 |
Medications Prior to Admission | ||||
No anti-platelet, (%) | 23 (49) | 9 (47) | 14 (50) | .86 |
Single anti-platelet, (%) | 21 (45) | 8 (42) | 13 (46) | .77 |
Dual anti-platelet, (%) | 3 (6) | 2 (11) | 1 (4) | .34 |
Statin therapy, (%) | 26 (55) | 10 (53) | 16 (57) | .76 |
Radiographic Infarct Pattern | ||||
Any watershed infarct, (%) | 22 (47) | 10 (53) | 12 (43) | .72 |
Any non-watershed infarct, (%) | 24 (51) | 13 (68) | 11 (39) | .08 |
Medications at the Time of Transcranial Doppler | ||||
Single anti-platelet, (%) | 37 (79) | 13 (68) | 24 (86) | .16 |
Dual anti-platelet, (%) | 6 (13) | 3 (16) | 3 (10) | .61 |
Clinical Outcomes | ||||
Mean duration of hospitalization (days) [SD] | 7 [4] | 6 [4] | 7 [4] | .12 |
Carotid revascularization procedure, (%) | 20 (43) | 1(5)* | 19(68) | <.001 |
Recurrent cerebral ischemia at ninety days, (%) | 9 (19) | 4 (21) | 5 (18) | .78 |
Death at ninety days, (%) | 1 (2) | 0 | 1 (3) | .41 |
One occlusion patient was noted to have partial vessel recanalization at 1 month and then underwent a carotid endarterectomy