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. 2018 Feb 8;3(3):e95417. doi: 10.1172/jci.insight.95417

Figure 5. CX3CR1-M280/M280 monocytes exhibit impaired AKT and ERK activation following CX3CL1 stimulation.

Figure 5

(A) Representative Western blots. (B and C) Quantitation of Western blot data. n = 5–7 (B), n = 8–13 (C). *P < 0.05; **P < 0.01; ****P < 0.0001. Statistical analysis was performed using an unpaired 2-tailed t test (with or without Welch’s correction) with the exception of the comparison of pERK/GADPH fold change at 3 minutes between CX3CR1-WT/WT and CX3CR1-M280/M280 which was performed using Mann-Whitney test. Quantitative data represent the mean ± SEM.