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(A) Scheme for mouse treatment for early time point analysis. (B) H&E, periodic acid–Schiff (PAS), and IHC for pERK in KC and KCip53 animals at 10 weeks of age. (C) Quantification of pancreatic pathology in KC and KCip53 animals, analyzed by 2-way ANOVA, presented as mean with SD. n = 3–6 animals per genotype. All histology magnification at ×20.
