Figure 7. Cytosolic lipid localization in skeletal muscle in endurance-trained athletes, lean controls, obese individuals, and individuals with type 2 diabetes.

Data are shown for DAG concentration (A), sphingolipid concentration (B), 1,2-DAG species, (C) ceramide species (D), sphingomyelin species (E), and lactosylceramide species (F). The box plot shows the median and 25th and 75th percentiles, and the whiskers represent the 10th and 90th percentiles. n = 16 athletes, 14 lean, 15 obese, and 12 T2D. CER, ceramides; DHCER, dihydroceramides; SPM, sphingomyelins; GluCER, glucosylceramides; LacCER, lactosylceramides. ^¥P < 0.05, compared with lean, ^#P < 0.05, compared with athletes, analyzed with 1-way ANOVA and corrected for multiple comparisons