Table 4.
Parameters | Estimate | Bootstrap median (95% CI) |
---|---|---|
CL (L/hr) | 29.0 | 28.8 (27.0 − 31.2) |
V1 (L) | 19.5 | 19.6 (17.2 − 24.1) |
Q (L/hr) | 28.6 | 28.2 (20.4 − 34.2) |
V2 (L) | 20.9 | 20.6 (18.3 − 23.2) |
CL, clearance; V1, volume of distribution into the central compartment; Q, inter-compartmental clearance; V2, volume of distribution into the peripheral compartment.