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(A) The effects of position-6 mismatches on slicing by miR-430–programmed hsAGO2. In vitro slicing assays were as in Figure 1D, plotted as in Figure 2D.
(B) The effects of position-6 mismatches on slicing by miR-430–programmed drAgo2. Otherwise, this panel is as in (A).
(C) The effects of position-6 mismatches on slicing by miR-451–programmed hsAGO2. Otherwise, this panel is as in (A).
See also Figure S6.
