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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Magn Reson Med. 2017 Oct 11;79(5):2766–2772. doi: 10.1002/mrm.26924

FIGURE 6.

FIGURE 6

The effect of agent concentration on pHe measurements with acidoCEST MRI. a) The average concentration of iopamidol in kidney, flank tumor and lung tumor estimated with Bloch fitting of pixelwise CEST spectra showed good uptake of agent in all three tissue types. Error bars represent the standard deviations of the distributions of pixels. The agent concentrations and pHe values were uncorrelated for b) kidney, c) flank xenograft tumor, and d) lung tumors on a pixelwise basis. Voxels where pHe data could not be fit were excluded. N = 3 mice for each tissue type.