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. Author manuscript; available in PMC: 2018 Feb 21.
Published in final edited form as: J Biopharm Stat. 2015;25(4):757–780. doi: 10.1080/10543406.2014.920871

Figure 2.

Figure 2

Illustration of a problem that may occur when the range of investigated doses includes doses that produce strong responses but is not wide enough to represent the overall dose-response relationship.