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. Author manuscript; available in PMC: 2018 Feb 21.
Published in final edited form as: J Biopharm Stat. 2015;25(4):757–780. doi: 10.1080/10543406.2014.920871

Figure 4.

Figure 4

Quantile-quantile (Q-Q) plot for model of detection limit estimated with virus-infection neutralization data. The points tend to align along a straight line with slope 1 and intercept 0, suggesting that pdf (10) is a reasonable model of the detection limit for percent neutralization responses, and therefore, that an estimated detection limit of 4.42% is reasonable for these responses. The Q-Q plot was made with 1 the points (F̂−1(i/m), T(i)), i = 1, …, 21 − 1, where T(1) ≤ … ≤ T(21) are the order statistics of the 21 transformed responses in Table 1 which were used to estimate the parameters α, β, θ and γ2 of pdf (10), and F̂ is an estimate of the cumulative distribution function corresponding to this pdf, which was computed with the maximum-likelihood estimates of these parameters.