Table 2.

Associations between depressive symptoms, two-year overall survival and potential behavioral and biological mediators.

Survival Analysis: Depressive Symptoms
Predictor	B	df	P	Hazard Ratio	95% CI
Depression	−0.141	1	<.001	0.868	0.819 – 0.921
Survival Mediation Analysis: Depressive Symptoms and Treatment Interruption
Predictors	B	df	P	Hazard Ratio	95% CI
Depression	−0.106	1	.026	0.900	0.819 – 0.987
Treatment Interruption	0.359	1	.527	1.432	0.471 – 4.351
Depression * Interruption	0.036	1	.703	1.036	0.863 – 1.245
Survival Mediation Analysis: Depressive Symptoms and Treatment Response
Predictors	B	df	P	Hazard Ratio	95% CI
Depression	−0.096	1	.005	0.908	0.849 – 0.971
Treatment Response	1.729	1	<.001	5.637	2.683 – 11.845
Depression * Response	0.098	1	.153	1.103	0.964 – 1.261

Note. All predictors were centered prior to analyses.