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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Cancer. 2017 Dec 13;124(5):899–906. doi: 10.1002/cncr.31144

Table 2.

3-year, 5-year and 8-year Cumulative Incidence (%) of AML/MDS by Chemotherapy Regimens*

AML

N patients 3-year Cumulative Incidence 5-year Cumulative Incidence 8-year Cumulative Incidence

N at Risk % (95% CI) N at Risk % (95% CI) N at Risk % (95% CI)
All Subjects 92,110
Chemo Regimen
 No Chemo 71,886 61,446 0.21 (0.18 – 0.25) 50,985 0.32 (0.13– 0.37) 27,697 0.45 (0.40 – 0.51)
 A-based 3,797 3,395 0.41 (0.25 – 0.68) 3,058 0.53 (0.34 – 0.83) 2,218 0.90 (0.62 – 1.30)
 A+T 8,338 7,316 0.40 (0.28 – 0.56) 6,165 0.61 (0.46 – 0.82) 3,546 0.84 (0.64 – 1.08)
 TC 3,083 2,794 0.13 (0.05 – 0.36) 2,186 0.17 (0.07 – 0.41) 566 0.22 (0.10 – 0.51)
 Other Taxane 2,851 2,215 0.23 (0.10 – 0.51) 1,690 0.33 (0.16 – 0.66) 560 0.33 (0.17 – 0.66)
 CMF 2,155 1,899 0.15 (0.05 – 0.45) 1,614 0.37 (0.18 – 0.79) 1,064 0.72 (0.41 – 1.28)

MDS

N patients 3-year Cumulative Incidence 5-year Cumulative Incidence 8-year Cumulative Incidence

N at Risk % (95% CI) N at Risk % (95% CI) N at Risk % (95% CI)

All Subjects 92,110
Chemo Regimen
 No Chemo 71,886 61,191 0.62 (0.56 – 0.68) 50,704 0.88 (0.81 – 0.96) 27,535 1.11 (1.03 – 1.20)
 A-based 3,797 3,362 1.26 (0.94 – 1.67) 3,021 1.72 (1.34 – 2.21) 2,190 2.24 (1.78 – 2.80)
 A+T 8,338 7,274 0.90 (0.71 – 1.13) 6,120 1.23 (1.00 – 1.50) 3,519 1.55 (1.28 – 1.87)
 TC 3,083 2,786 0.47 (0.28 – 0.79) 2,175 0.67 (0.42 – 1.04) 562 0.91 (0.59 – 1.38)
 Other Taxane 2,851 2,195 1.07 (0.74 – 1.55) 1,671 1.38 (0.99 – 1.94) 553 1.66 (1.20 – 2.30)
 CMF 2,155 1,882 0.97 (0.62 – 1.49) 1,593 1.37 (0.94 – 1.99) 1,050 2.19 (1.78 – 2.80)
*

Estimated from Kaplan-Meier Method; CI - Confidence Interval