TABLE 3.

Medical conditions reported by Hormone Therapy trial participants postintervention, by sexual activity status^a

	Sexually activeb n =4414		Sexually inactive n=7356		Did not respond n=2132
	n	%	n	%	n	%	Pc
History of cancer	187	4.2	404	5.5	111	5.2	0.003
History of myocardial infarction	101	2.3	232	3.2	69	3.2	0.006
History of congestive heart failure	47	1.1	133	1.8	45	2.1	0.001
History of diabetes mellitus	384	8.7	866	11.8	290	13.6	<0.001
History of hyperlipidemia	1007	22.8	2037	27.7	619	29.0	<0.001
History of hypertension	1953	44.2	3874	52.7	1137	53.3	<0.001
History of arthritis	2208	50.0	4286	58.3	1186	55.6	<0.001
History of hysterectomy	1173	26.6	2591	35.2	903	42.4	<0.001
History of bilateral oophorectomy	402	9.1	1017	13.8	313	14.7	<0.001
History moderate/severe urine leakage	1576	35.7	2975	40.4	749	35.1	<0.001
History of antidepressant use	416	9.4	957	13.0	226	10.6	<0.001
Depression construct (0–18), mean (SD)d	2.1 (2.3)		2.5 (2.7)		2.5 (2.6)		<0.001
Poor to fair self-rated health	198	4.5	731	9.9	229	10.7	<0.001
Quality of life (0–10), mean (SD)e	8.3 (1.5)		7.9 (1.7)		8.0 (1.7)		<0.001

^aBased on most recent assessment with exception of bilateral oophorectomy which was assessed at original Women’s Health Initiative study enrollment baseline.

^bSexually active includes activity with a partner or self-stimulation. Estrogen-Progestin Therapy trial participants were asked “Has sexual activity been part of your life since you stopped study pills”; Estrogen Therapy trial participants were asked “Has sexual activity been part of your life in the last 3 months?”

^cP value compares sexually active vs. inactive.

^dHigher score indicates greater depression.

^eHigher score indicates better quality of life.

SD, standard deviation.