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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Magn Reson Med. 2017 Sep 14;79(5):2470–2480. doi: 10.1002/mrm.26901

Figure 7.

Figure 7

Data from an astrocytoma patient with recurrent tumor is shown. For clarity, every other slice from the superior 2 cm is shown. There is widespread Ch/NAA and Cr/NAA (not shown) abnormality. (A,B) Using a standard error of regression at 0.14 for Ch/NAA shows the more extensive abnormalities in comparison to a standard error of 0.18. (C) Reducing the total brain filter criterion to 10% does not introduce erroneous voxels, while the lesion is more consistently detected. Based on the MP2RAGE image alone, there is mis-segmentation of the right central parietal tumor region as CSF; to include these areas in this MRSI analysis, the tissue classification of these tumor regions was assigned to 100% white matter; the severity of Ch/NAA abnormality in this region remains. (D,E) demonstrate the loss of pixels when filtered at a total brain of 10 vs. 65%. The anatomy is shown with the MP2RAGE and FLAIR images (F,G).