Author |
Number of |
FU |
Annual |
ECG finding |
HR (95% CI, P-value) |
(Rf. No.) |
participants |
time |
incidence |
|
|
P-wave duration |
|
|
|
|
|
Perez
[13] |
42,751 |
5.3 yrs |
0.45% |
>120 ms |
1.6 (1.3-1.8, P<0.0001) |
|
|
|
|
per 20 ms |
1.1 4 (1.02-1.27, P=0.022) |
Soliman[14] |
15,429 |
6.97 yrs |
0.11% |
>120 ms |
1.94 (1.66-2.28) Model 1 |
|
|
|
|
|
1.79 (1.51-2.14) Model 2 |
|
|
|
|
Upper 5% |
5.23 (3.33-8.22) Model 1 |
|
|
|
|
|
4.07 (2.55 - 6.51) Model 2 |
Magnani[15] |
1,550 |
15.8 yrs |
1.46% |
Upper 5% |
2.51 (1.13-5.57) |
|
|
|
|
per 1 SD |
1.1 (0.90-1.47, P=0.27) |
Nielsen[28] |
285,933 |
6.7 yrs |
0.49% |
>89 ms |
1.60 (1.41−1.81 P<0.001) |
|
|
|
|
100-105 ms |
1.00 |
|
|
|
|
112-119 ms |
1.22 |
|
|
|
|
120-129 ms |
1.50 |
|
|
|
|
≥130 |
2.06 |
P-wave dispersion |
|
|
|
|
|
Perez
[13] |
- |
- |
- |
>80 ms |
1.95 (1.7-2.3, P<0.0001) |
|
|
|
|
SD of P duration >35 |
1.7 (1.3-2.1, P<0.0001) |
P-morphology |
|
|
|
|
|
Soliman[14] |
- |
- |
- |
95th% of PTFV1 |
1.23 (1.04-1.46) |
Magnani[16] |
- |
- |
- |
PTFV1 >0.04 V•s |
1.56 (1.24-2.00) |
Enriquez[35] |
122 |
30 mo |
46.7% |
P duration ≥120 ms |
2.9 (1.02-8.6, P<0.04) |
|
|
|
|
Biphasic P in II,I II, aVF |
|
Abn. P axis |
|
|
|
|
|
Perez
[13] |
- |
- |
- |
>95th% |
1.21 (0.69-2.12, P<0.0001) |
|
|
|
|
>74° and <24° |
1.52 (1.05-2.21, P>0.0001 |
PAC/runs |
|
|
|
|
|
Watanabe
[51] |
63,368 |
10 yrs |
0.14% |
Standard ECG, ≥1/10 sec |
2.89 (1.80-3.35) |
Perez
[13] |
- |
- |
- |
Presence |
2.1 (1.6-2.7, P<0.0001) |
Murakoshi [52] |
63,197 |
14 yrs |
0.105% |
Presence |
4.87 (6.61-6.57) for men |
|
|
|
|
|
3.87 (2.69-5.57) for women |
Acharya[56] |
1,357 |
7.5 yrs |
11.4% |
≥100/day |
2.97 (1.85-4.80) |
|
|
|
|
couplets ≥50/day |
3.11 |
|
|
|
|
bigeminy |
3.67 |
|
|
|
|
3 PACs run ≥20 /day |
2.94 |
|
|
|
|
runs (≥10 beats/run) |
1.73 |
PR interval |
|
|
|
|
|
Perez [13] |
- |
- |
- |
>200 ms |
1.3 (1.1-1.6, P=0.003) |
Nielsen[69] |
288,181 |
6.7 yrs |
3.8% |
≥196 ms men |
1.30 (1.17-1.44) |
|
|
|
|
≥204 ms women |
1.18 (1.06-1.530) |
|
|
|
|
<129 ms men |
1.09 (0.92-1.29) ‡ |
|
|
|
|
<121 ms women |
1. 32 (1.12-1.56) |
Alonso[25] |
262,288 |
5 yrs |
6.8% |
per 30 ms |
1.03 (0.85-1.26, <0.0001) |
|
|
|
|
|
to 1.22 (1.01-1.42, 0.027) |
Macfarlane[68] |
5,680 |
3.2 yrs |
9.4% |
per 30 ms |
1.19 (1.09-1.30, P<0.0001) |