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. 2017 Dec 31;10(4):1805. doi: 10.4022/jafib.1805

Table 1. Baseline Characteristics between Dofetilide and Sotalol groups (n = 378).

Data were represented as mean ± standard deviation or counts (percentage)

Characteristics Dofetilide (n = 298) Sotalol (n = 80) p value
Demographics
Age (years) 64 ± 10.3 64 ± 11.6 0.46
Gender: Male (%) 205 (68.8%) 46 (57.5%) 0.06
Race: Caucasian (%) 270 (90.6%) 71 (88.7%) 0.14
Body Mass Index (BMI) 33 ± 7.4 33 ± 7.8 0.90
Co morbidities
Paroxysmal AF 183 (61.4%) 50 (62.5%) 0.22
Hypertension 252 (84.5%) 67 (83.7%) 1.00
Diabetes mellitus 63 (21.1%) 20 (25%) 0.45
Hyperlipidemia 218 (73.1%) 66 (82.5%) 0.08
Coronary artery disease 93 (31.2%) 41 (51.2%) 0.001
Stroke/Transient ischemic attack 25 (8.4%) 10 (12.5%) 0.10
Medication
Beta Blockers 89 (29.0%) 28 (35.0%) 0.57
Calcium Channel Blocker 165 (55.5%) 56 (70.0%) 0.01
ACE Inhibitor/ARB 89 (29.0%) 28 (35.0%) 0.57
Labs
Creatinine Clearance (ml/min) 105.2 ± 41.2 102.3 ± 37.4 0.58
Baseline Potassium level (mEq/L) 4.12 ± 0.41 4.17 ± 0.36 0.90
Baseline Magnesium level (mEq/L) 2.11 ± 1.1 2.0 ± 0.18 0.38
EKG/Echo
Sinus rhythm on arrival 83 (27.8%) 32 (40%) 0.03
Baseline QTc (msec) 448.9 ± 33.2 444 ± 42.6 0.35
Left Atrial Size (cm) 4.53 ± 0.8 5.45 ± 0.60 0.73
Left ventricle Ejection Fraction (%) 51.7 ± 12 52.5 ± 12.6 0.65