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. 2017 Dec 31;10(4):1805. doi: 10.4022/jafib.1805

Table 3. Safety outcomes between Dofetilide and Sotalol groups - Adverse events (n = 378).

Data were represented as counts (percentage)

Adverse events Dofetilide (n = 298) Sotalol (n = 80) p value
Bradyarrhythmias
Bradycardia (HR < 60) 22 (7.4%) 9 (11.3%) 0.26
Sinus pause > 2 secs 0 (0%) 0 (0%) -
High grade AVB 6 (2.0%) 2 (2.5%) 0.67
Ventricular arrhythmias
New onset PVCs 0 (0%)) 0 (0%) -
Non Sustained VT 7 (2.3%) 1 (1.3%) 1.00
Torsades de pointes (TdP) 4 (1.3%) 1 (1.2%) 1.00
Ventricular fibrillation (VF) 0 (0%) 0 (0%) -
Drug Discontinuation 24 (8.8%) 4 (5%) 0.47