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. 2018 Feb 27;71(8):860–871. doi: 10.1016/j.jacc.2017.12.035

Figure 2.

Figure 2

Cell and Matrix Remodeling 1 Year After AVR

(A) At 1-year post–aortic valve replacement (AVR), there was a 19% reduction in indexed left ventricular (LV) mass (88 ± 26 g/m2 to 71 ± 19 g/m2; p < 0.001) (B) The extracellular volume fraction (ECV) increased unexpectedly from 28.2 ± 2.9% to 29.9 ± 4.0% (p < 0.001). (C) Derived indexed cell volume (left ventricular mass index × [1 − ECV]) reduced by 22% (64 ± 18 ml/m2 to 50 ± 13 ml/m2; p < 0.001), and (D) derived indexed matrix volume (left ventricular mass index × ECV) reduced by 16% (25 ± 9 ml/m2 to 21 ± 7 ml/m2; p < 0.001).