Table 1.
Baseline Clinical Characteristics (N = 116)
| Age, yrs | 70 ± 10 |
| Male | 63 (54) |
| Trileaflet | 83 (72) |
| Bicuspid∗ | 33 (28) |
| BSA, m2 | 1.90 ± 0.22 |
| Comorbidities | |
| Hypertension | 87 (75) |
| SBP, mm Hg | 133 ± 17 |
| DBP, mm Hg | 76 ± 10 |
| Diabetes | 23 (20) |
| Coronary artery disease | 34 (29) |
| Atrial fibrillation | 16 (14) |
| Risk scores | |
| STS, % | 1.3 (1.0–2.1) |
| EuroSCORE II, % | 1.4 (1.0–2.4) |
| Drug history | |
| ACE inhibitor/ARB | 51 (44) |
| Beta-blocker | 43 (37) |
| Statin | 74 (64) |
| Aspirin | 51 (44) |
| Blood | |
| Creatinine, μmol/l | 85 ± 26 |
| eGFR, ml/min/1.73 m2 | 77 ± 21 |
| Hematocrit, % | 40.4 ± 4.5 |
| Histology | |
| Collagen volume fraction, %† | 7.7 (4.2–12.7) |
Values are mean ± SD, n (%), or median (interquartile range).
ACE = angiotensin-converting-enzyme; ARB = angiotensin receptor blocker; BSA = body surface area; DBP = diastolic blood pressure; eGFR = estimated glomerular filtration rate; EuroSCORE II = European System for Cardiac Operative Risk Evaluation II score; IQR = interquartile range; LVH = left ventricular hypertrophy; NYHA = New York Heart Association; SBP = systolic blood pressure; STS = The Society of Thoracic Surgeons risk model score.
∗
One patient had unicuspid aortic stenosis (female).
†
n = 91.