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. 2018 Feb 21;8:3417. doi: 10.1038/s41598-018-21730-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Exponent analysis for folate reared cultures. Same as in Fig. 3 but for a characteristic folate reared culture. For this recording, the ISI is 220 ms corresponding to a bin size of about 7. The critical exponents are τ_folate = 2.2 ± 0.2, α_folate = 3.3 ± 0.4 and γ_folate = 0.5 ± 0.1 for bin size 7. The values of τ_folate and α_folate significantly differ from those for control cultures (see Fig. 3) and what is predicted by mean-field theory. Yet, they are still consistent with the scaling relation (4). See Materials and Methods for an extended analysis.