Table 3.
Univariate and multivariate analysis for risk factors influencing survival in patients diagnosed with pancreatic cancer.
| Variable | Univariate | Variable | Multivariate | ||
|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | ||
| CEMIP, mg/dL | CEMIP, mg/dL | ||||
| <0.429 | Ref. | <0.429 | Ref. | ||
| ≥0.429 | 1.378 (1.056-1.798) | 0.018 | ≥0.429 | 1.646 (1.224–2.214) | 0.001 |
| Age | 1.022 (1.010–1.035) | 0.001 | Age | 1.022 (1.009–1.036) | 0.001 |
| Sex | |||||
| Women | Ref. | ||||
| Men | 1.219 (0.957–1.552) | 0.108 | |||
| Diabetes mellitus | |||||
| No | Ref. | ||||
| Yes | 0.947 (0.729–1.229) | 0.680 | |||
| Treatment | Treatment | ||||
| Supportive care | Ref. | No | Ref. | ||
| Chemotherapy | 0.521 (0.280–0.970) | 0.039 | Yes | 0.243 (0.128–0.462) | <0.001 |
| Operation | 0.134 (0.069–0.263) | <0.001 | |||
| Location of cancer | |||||
| Head | Ref. | ||||
| Body | 1.372 (1.013–1.859) | 0.041 | |||
| Tail | 1.444 (1.049–1.986) | 0.024 | |||
| Mixed | 1.344 (0.883–2.045) | 0.167 | |||
| Stage | Stage | ||||
| I and II | Ref. | I and II | Ref. | ||
| III | 1.228 (0.862–1.748) | 0.254 | III | 1.733 (1.137–2.639) | 0.011 |
| IV | 3.754 (2.807–5.020) | <0.001 | IV | 5.310 (3.663–7.696) | <0.001 |
A P-value < 0.02 was considered statistically significant. We found the cut-off point to maximize the survival curve using Contal and O’Quigley’s method.
HR, hazard ratio; CI, confidence interval.