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. 2018 Feb 21;9:754. doi: 10.1038/s41467-018-02891-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Evidence of clonal expansion during cardiac development. Representative fluorescent microscope images of a–c, Mesp1^Cre; R26^VT2/GK, d–f, Nkx2.5^Cre; R26^VT2/GK, and g–i, αMHC^Cre; R26^VT2/GK longitudinal hearts sections at E14.5, P1, and P21 respectively (n = 4). Insets show a higher magnification of boxed areas. Putative clonal areas are traced by a dotted line. Scale bar 500 μm (c, f, i), all others 50 μm