Table 1.
Clinical characteristics of PE and control groups.
| Characteristic | Control (n = 40) | PE (n = 35) | p-value |
|---|---|---|---|
| Maternal age, years (IQR) | 31.3 (25.9–34.6) | 29.9 (28.1–34.5) | 0.9200 |
| Body Mass Index, kg/m2 (IQR) | 24.1 (22.6–28.7) | 28.4 (24.4–31.7) | 0.0125 |
| Gestational age, weeks (IQR) | 12.8 (12.3–13.2) | 12.7 (12.2–13.1) | 0.3916 |
| Crown-rump length, mm (IQR) | 63.9 (57.5–70.2) | 62.9 (56.2–67.9) | 0.3029 |
| Mean arterial pressure (MAP), mm Hg (IQR) | 83.2 (79.4–87.7) | 97.1 (90.1–108.7) | <0.0001 |
| Uterine artery pulsatility index (UT PI) (IQR) | 1.5 (1.3–1.7) | 2.5 (2–2.8) | <0.0001 |
| Gestational age at delivery, weeks (IQR) | 39.8 (39.4–40.7) | 31.4 (29.4–33.2) | <0.0001 |
| Birth weight, g (IQR) | 3,420 (3,198–3,578) | 1,222 (951–1,565) | <0.0001 |
| Fetal Gender, n(%) | 0.65 | ||
| female | 22 (55) | 17 (42.5) | |
| male | 18 (45) | 18 (45) | |
| Ethnicity, n(%) | 0.2848 | ||
| Afro-Caribbean | 15 (37.5) | 19 (54.3) | |
| South Asian | 1 (2.5) | 1 (2.9) | |
| Caucasian | 24 (60) | 15 (42.9) | |
| Cigarette smokers, n(%) | 0.11 | ||
| No smoker | 34 (85) | 34 (97.1) | |
| Smoker | 6 (15) | 1 (2.9) | |
| Family history of preeclampsia, n(%) | 0.41 | ||
| Yes | 2 (5) | 4 (11.4) | |
| No | 38 (95) | 31 (88.6) | |
| Parity, n(%) | 0.0018 | ||
| Multiparous with no previous PE | 15 (37.5) | 6 (17.1) | |
| Multiparous with previous PE | 0 (0) | 8 (22.9) | |
| Nulliparous | 25 (62.5) | 21 (60) | |
| Chronic hypertension, n(%) | 0.001 | ||
| Yes | 0 (0) | 8 (22.9) | |
| No | 40 (100) | 27 (77.1) |
A comparison of maternal and pregnancy characteristics between the two groups: pregnant women that have developed preeclampsia (PE) and pregnant women with uncomplicated pregnancies (control). P-values were calculated using Fisher exact test for categorical variables, and using Mann-Whitney U test for continuous variables.