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. 2018 Feb 21;8:3438. doi: 10.1038/s41598-018-21720-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Impact of Malat1 on kidney function and survival after bilateral renal I/R injury. Creatinine levels in Malat1 knockout and wildtype mice before induction of ischemia/reperfusion injury, 1 day after ischemia/reperfusion injury, 3 days after ischemia/reperfusion injury and 7 days after ischemia/reperfusion injury (A). Urea levels in Malat1 knockout and wildtype mice before induction of ischemia/reperfusion injury, 1 day after ischemia/reperfusion injury, 3 days after ischemia/reperfusion injury and 7 days after ischemia/reperfusion injury (B). Survival study in Malat1 knockout- and wildtype mice after bilateral renal ischemia/reperfusion injury (C). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. KO = knockout, WT = wildtype. n = 10 mice in each group.