Figure 4. ABCB4 is significantly associated with clinical prognosis.
(A) ABCB4 was significantly down-regulated in the tumor tissues from TCGA(COADREAD) cohort; P<0.0001. (B) ABCB4 was down-regulated in the recurrent tissues compared with the first primary tumor. P-tumor represents the first primary tumor and R-tumor represents the corresponding recurrent tumor; P=0.039. (C) Kaplan–Meier curves showed that ABCB4 expression is significantly associated with a shorter recurrence-free survival in CRC patients; Log-rank P<0.01. (D) Kaplan–Meier curves showed that ABCB4 expression is significantly associated with a shorter overall survival in CRC patients; Log-rank P=0.03.