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Chemotherapy for osteosarcoma patients in the present study.
| Drug dose | Flowchart | ||
|---|---|---|---|
| Drug | Drug, mg/m2/cycle | Day | Drug |
| (1) Neoadjuvant chemotherapy (3 cycles) | First cycle | ||
| DDP | 80 | 1 | DDP |
| CTX | 540 | 3 | CTX + VCR |
| VCR | 1 | 15 | ADR |
| ADR | 40 | 16 | ADR |
| (2) Surgery | Second cycle | ||
| (3) Adjuvant chemotherapy (4 cycles) | 29 | DDP | |
| DDP | 80 | 31 | CTX + VCR |
| CTX | 540 | 43 | ADR |
| VCR | 1 | 44 | ADR |
| ADR | 40 | And so on | |
DDP = cisplatin; CTX = cyclophosphamide; VCR = vincristine; ADR = adriamycin.
