Table 1. Univariate Risk Factor Analysisa.
| Variable | Proportion With Sz (95% CI) | No. (%) of Patients With Finding | OR (95% CI) | P Valueb |
|---|---|---|---|---|
| PDR | 0.10 (0.08-0.12) | 1166 (21.5) | 0.711 (0.50-0.92) | <.001 |
| BRDs | 0.69 (0.62-0.76) | 176 (3.2) | 18.805 (18.47-19.14) | <.001 |
| Unreactive background | 0.18 (0.15-0.22) | 454 (8.4) | 1.610 (1.36-1.86) | <.001 |
| Prior Sz | 0.23 (0.20-0.25) | 1168 (21.5) | 2.663 (2.50-2.83) | <.001 |
| GRDA | 0.13 (0.11-0.15) | 927 (17.1) | 1.071 (0.862-1.28) | .51 |
| LRDA | 0.28 (0.23-0.32) | 410 (7.6) | 2.967 (2.73-3.20) | <.001 |
| GPDs | 0.16 (0.13-19) | 696 (12.8) | 1.368 (1.15-1.59) | <.01 |
| LPDs | 0.44 (0.41-0.48) | 802 (14.8) | 9.825 (9.65-10.0) | <.001 |
| BIPDs | 0.28 (0.21-0.36) | 122 (2.2) | 2.784 (2.38-3.19) | <.001 |
| Infection | 0.16 (0.11-0.24) | 118 (2.2) | 1.350 (0.853-1.85) | .26 |
| Inflammation | 0.13 (0.06-0.24) | 56 (1.0) | 0.998 (0.202-1.80) | .99 |
| Neoplasm | 0.19 (0.16-0.22) | 577 (10.6) | 1.694 (1.47-1.92) | <.001 |
| ICH | 0.12 (0.10-0.15) | 543 (10.0) | 0.963 (0.693-1.23) | .84 |
| Metabolic encephalopathy | 0.06 (0.04-0.10) | 325 (6.0) | 0.467 (0.0177-0.916) | <.001 |
| Stroke | 0.10 (0.07-0.13) | 452 (8.3) | 0.737 (0.416-1.059) | .06 |
| SAH | 0.07 (0.05-0.09) | 508 (9.4) | 0.499 (0.140-0.845) | <.001 |
| SDH | 0.13 (0.10-0.17) | 353 (6.5) | 1.078 (0.760-1.40) | .62 |
| TBI | 0.07 (0.04-0.12) | 142 (2.6) | 0.523 (0-1.170) | .05 |
| Hypoxic/ischemic | 0.13 (0.10-0.16) | 390 (7.2) | 1.004 (0.694-1.311) | .99 |
| IVH | 0.10 (0.06-015) | 146 (2.7) | 0.736 (0.180-1.29) | .31 |
| Hydrocephalus | 0.07 (0.03-0.14) | 86 (1.6) | 0.520 (0-1.35) | .14 |
| Discharges | 0.29 (0.26-0.33) | 763 (14.1) | 3.733 (3.55-3.91) | <.001 |
| Frequency (>2Hz)c | 0.42 (0.32-53) | 77 (1.4) | 2.570 (1.62-4.09) | <.001 |
Abbreviations: BIPD, bilateral periodic discharges; BRDs, brief rhythmic discharges; GPDs, generalized periodic discharges; GRDA, generalized rhythmic delta activity; ICH, intracranial hemorrhage; IVH, intraventricular hemorrhage; LPDs, lateralized periodic discharges; LRDA, lateralized rhythmic delta activity; OR, odds ratio; PDR, posterior dominant rhythm; Prop, proportion with seizures; SAH, subarachnoid hemorrhage; SDH, subdural hemorrhage; Sz, seizure; TBI, traumatic brain injury.
a
A total of 2868 were men (49.9%), median age; 61 years.
b
P value calculated with Fisher exact test.
c
Variable only evaluated for ictal-interical continuum patterns.