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. 2017 Aug 28;74(10):1266–1267. doi: 10.1001/jamaneurol.2017.2122

Table. Patient Demographics and Treatment Response to Noninvasive Vagus Nerve Stimulation.

Sex/Age, y Laterality Treatment Response Treatment Durationa
Hemicrania Continua
Male, 49 Left Persistent pain reduced by 60% 2 y and 8 mo
Man, 37 Left Persistent pain reduced by 40% 2 y
Female, 55 Left Persistent pain reduced by 80% 5 y
Female, 27 Left Persistent pain reduced by 50% or more, exacerbations reduced from 4 per wk to 2 per mo; acute treatment (1 dose) reduced severity and duration from 48-72 h to 12-24 h 1 y
Female, 42 Left Persistent pain reduced by 15%, exacerbation duration reduced from days to 1 h 6 mo
Female, 23 Left Persistent pain reduced by 30% 2 y and 4 mo
Female, 53 Right Persistent pain reduced by 30%-50%, exacerbations reduced from 15 per mo to 1 every 2 mo; acute treatment (6-8 doses) reduced severity by 40% and duration from >24 h to <24 h 5 mo
Female, 38 Right No response 3 mo
Male, 61 Left No response 6 mo
Paroxysmal Hemicrania
Female, 43 Left Attack frequency reduced from 12 to 4 per d, reduced severity and duration from 20-40 min to 10 min 3 mo
Female, 47 Right “Dramatic” reduction in frequency and severity 1 y and 8 mo
Female, 48 Left Complete cessation of attacks 1 y and 3 mo
Female, 29 Right Decreased severity 5 y
Male, 54 Left No response 4 mo
Female, 38 Right No response 4 mo
a

At time of last follow-up.