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. 2017 Feb 27;74(5). doi: 10.1001/jamaneurol.2016.5042

Table 2. Hazard of Developing Epilepsy Among Those Patients Treated for Depression (Counselling and/or Medical Treatment)a.

Risk Factor HR (95% CI) P Value
Treatment for depression 3.42 (3.37-3.47) <.001
Age at index date 1.02 (1.02-1.02) <.001
Female sex 1.01 (1.01-1.03) .03
Townsend Deprivation Index 1.09 (1.08-1.10) <.001
Charlson Comorbidity Index 1.30 (1.29-1.31) <.001
a

Treatment for major depressive disorder was considered as a time-varying covariate in this Cox proportional hazards regression analysis. The hazard ratio (HR) for age, Townsend Deprivation Index, and Charlson Comorbidity Index is for each incremental increase in value. Higher values indicate more social deprivation and a larger number of comorbidities.