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. 2017 Apr 24;74(6):677–685. doi: 10.1001/jamaneurol.2017.0357

Figure 2. Expression of Inflammation-Related Differentially Expressed Genes Verified by Quantitative Reverse Transcription Polymerase Chain Reaction .

Figure 2.

Upregulation of IL1B (A), NLRP3 (B), IL8 (C), FOSB (D), CD83 (E), SOCS3 (F), CXCL1 (G), and CXCL2 (H) in monocytes of patients with amyotrophic lateral sclerosis (ALS) (n = 43) were verified by quantitative reverse transcription polymerase chain reaction. Arbitrary unit of each mRNA was normalized to β-actin and relative to the healthy control (HC) samples (n = 22). Error bars indicate the standard error.

aP < .01 vs HC (IL1B, P < .001; NLRP3, P = .007; IL8, P = .002; FOSB, P = .009; and CXCL1, P = .002).

bP < .05 vs HC (CD83, P = .02; SOCS3, P = .01; and CXCL2, P = .01).