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. 2017 Jul 17;74(9):1141–1143. doi: 10.1001/jamaneurol.2017.1460

Table. Patient Demographic and Clinical Characteristics and Lumbar Puncture Findingsa.

Patient No./Sex/Age, y Length of ETU Stay, d Time From ETU Discharge to LP, d Neurologic Symptoms Abnormal Neurologic Examination Findings CSF Measurement
During ETU Stay Since EVD Discharge WBCs/hpf RBCs/hpf Protein Level, mg/dL Glucose Level, mg/dL
1/Female/28 21 364 Hallucinations, confusion, headache, vision change Paresthesias, hallucinations, headache, memory loss, confusion Frontal release signs (glabellar, grasp), choppy pursuits, dysmetric saccades, increased reflexes 0 0 25.5 47.2
2/Male/23 8 459 Headache, AMS, hallucinations, vertigo, paresthesias New headache Cerebellar findings (dysmetria, dysdiadochokinesia), slowed saccades to left and left extinguishing horizontal nystagmus 0 0 18.2 58.7
3/Male/50 32 414 Headache, hallucinations, AMS, tremor, vertigo, tinnitus, paresthesias Memory loss, tinnitus Mild action tremor, peripheral neuropathy 0 0 17.9 53.6
4/Female/22 19 418 Headache, confusion, hallucinations, bilateral LE weakness and numbness Headache, memory loss, depression Choppy smooth pursuits, slowed saccades, decreased hearing, increased reflexes (3+ at knees) 0 0 42.5 61.5
5/Male/44 26 401 Headache, neck stiffness, AMS, hallucinations, paresthesias, tremor, hearing loss, vertigo New headache, memory loss, paresthesias Loss of sensation in V2 and V3, facial weakness, decreased hearing, mild postural tremor, peripheral neuropathy 0 0 30.7 44.5
6/Male/25 23 404 Headache, hallucinations, tremor, paresthesias, vertigo New headache, paresthesias Choppy pursuits, slowed saccades, tongue deviation, mild postural tremor, sensory neuropathy 0 0 31.8 69.9
7/Male/46 13 415 Headache, neck stiffness, double vision, hearing loss, vertigo, tinnitus, trouble swallowing, LOC, confusion Paresthesias, new headache, memory loss Parkinsonism with bradykinesia, mild cogwheeling and retropulsion; slowed saccades 3 2850 40.2 64.1

Abbreviations: AMS, altered mental state; CSF, cerebrospinal fluid; ETU, Ebola treatment unit; EVD, Ebola virus disease; hpf, high-powered field; LE, lower extremity; LOC, loss of consciousness; RBCs, red blood cells; WBCs, white blood cells.

SI conversion factors: To convert glucose to millimoles per liter, multiply by 0.0555; protein to grams per liter, multiply by 0.01.

a

Ebola virus was not detected on reverse transcriptase–polymerase chain reaction results using the GeneXpert (Cepheid) or ABI 7500 (Applied Biosciences) device in any patient.