Figure 4. Levels of PhIP-DNA adduct in paired fresh frozen prostate and FFPE blocks of six patients.
The levels of adducts are reported as adducts per 108 nucleotides. Two independent analyses were done per subject; *p < 0.02, n.s.: statistically not significant. DNA isolation from frozen and FFPE prostate tissues of six patients were performed using conventional phenol-chloroform extraction and MXF kit, respectively. All measurements were performed in duplicate and reported as the mean ± SD.